Anaplastic large-cell lymphoma
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Anaplastic large-cell lymphoma
Anaplastic large cell lymphoma, aggressiverelates to a class of T-cell lymphomas, wherein mainly swollen lymph nodes. Name indicatesthat the tumor is composed of T-cells and T-cells (T-lymphocytes) - the most formidable fightersimmunity, since they destroy foreign bacteria and patients own cells. At each stage, may failand the patient education group of tumor cells.When anaplastic lymphoma tumor cells sochanged that completely lose all signs of aging and look as young cells. This is indicated by the word "anaplasia." Lymph nodes in this diseaseincreases groups in the neck, armpits, groin, and elsewhere. The patient can be confusing andsuch signs of the disease, called "B symptoms": he has a fever, he is losing weight quickly and strongly in the evening and night sweats.Autoimmune complications are also possible, iefaulty immune response to its own tissues and organs of the body, when the protective system starts to work againsthealthy cells.


To make a correct diagnosis, certainly take a bit of a tumor or enlarged lymph node for morphological andimmunohistochemical study. It is very important for prognosis and treatment selection. Only such a complex,comprehensive analysis allows accurate diagnosis and effective treatment of conduct.

To accurately know whether enlarged lymph nodes and what is their number in those parts of the body that can not be seen by external examination, it is necessary to do a CT scan. Stage of the disease set by the system «Ann-Arbor», which reflects what organs and lymph nodes affected.


Treatment of anaplastic large cell lymphoma depends on the presence or absence of tumor enzyme called «ALK». Revealit during immunohistochemical study of lymph node. If the enzyme ALK is, lymphoma called ALK-positive. Theselymphomas are treated successfully in 70% of cases. If softer, relatively small doses of medicines can not cure the patient, it is carried out with the support of chemotherapy vysokodozirovannuyu own cells. If ALK enzyme is not present,lymphoma called ALK-negative. Results of treatment of ALK-negative lymphomas slightly worse, but there are always newdrugs that help to improve the treatment of these patients.

Dixion firm works closely with cancer centers in Germany, where the medication is used for the latest advances in medicine.
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