Loffler's syndrome (Loffler syndromus) - syndrome, pulmonary infiltration with eosinophilia. Most common inchildren suffering from allergic skin diseases (urticaria, eczema) and helminthiasis, amoebiasis or hypersensitivity to drugs (antibiotics, sulfonamides), plant allergens (pollen, etc.).

The reason is due to hypersensitivity syndrome vascular system to various allergens. And more susceptible toallergens small vessels and capillaries. Inflammation in these vessels leads to an increase in their permeability, which leads to formation of transient pulmonary eosinophilic infiltrates the migratory nature of which are clearly visible on radiographs.

The clinical picture

Develop skin rashes in the form of blisters, sometimes a maculopapular nature and swelling.

Patients complain of a general state of disorder, namely, fever, malaise, cough, shortness of breath.
Tsindrom may be accompanied by asthma attacks, joint pain, swollen lymph nodes often.

In analyzes of blood and sputum a marked eosinophilia.

Differential diagnosis is carried out with hives, no observed pulmonary eosinophilic infiltrates and no symptomsof cough, shortness of breath, asthma attacks.