Transurethral needle ablation (Also called TUNA or transurethral radiofrequency ablation) is a technique that uses low energy radio frequency energy delivered through two needles to ablate (destroy) excess prostate tissue. The energy from the probe heats and destroys the abnormal prostate tissue without damaging the urethra. It can be done with a local anesthetic on an outpatient basis. A catheter that deploys the needles toward the obstructing prostate tissue is inserted into the urethra directly through the penis under local anesthetic before the procedure begins. Transurethral needle ablation can be used to treat benign prostatic hypertrophy (BPH).

Some clinical studies have reported that TUNA is safe and effective, improving the urine flow with minimal side effects when compared with other procedures. However, other studies have reported that the procedure has a high failure rate, with the majority of patients requiring re-treatment.